SITI ROFIAINI, NIM. C12020046 (2026) POLA PENGOBATAN KANKER PAYUDARA DENGAN PRE DAN KEMOTERAPI PADA PASIEN RAWAT JALAN PESERTA JKN KANKER PAYUDARA DI RS PKU MUHAMMADIYAH GOMBONG PERIODE TAHUN 2023. Skripsi thesis, UNIVERSITAS MUHAMMADIYAH GOMBONG.

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Abstract

Background: Breast cancer is one of the most common cancers in women and requires chemotherapy, which often causes side effects, necessitating pre- chemotherapy therapy. Evaluating pre- and chemotherapy treatment patterns is important to determine the rationality of drug use in National Health Insurance patients. Research Objective: This study aims to determine the pre- chemotherapy and chemotherapy treatment patterns in outpatient breast cancer patients participating in National Health Insurance at PKU Muhammadiyah Gombong Hospital in the period of 2023. The analysis was conducted descriptively on patient characteristics and patterns of pre -chemotherapy drug use and chemotherapy regimens. Research Methods : This study used a descriptive observational design with a retrospective approach . Data were obtained from medical records of outpatient breast cancer patients from January–December 2023 using a purposive sampling technique and a sample size of 87 patients. Research Results : The results showed that the largest age group was 46–65 years old with 49 patients (56%), with the most common stage being breast cancer. dextra Grade III was 31 patients (36%), and the majority were National Health Insurance PBI participants (56 patients). All patients (100%) received pre- chemotherapy therapy in the form of a combination of dexamethasone , ondansetron , diphenhydramine , and ranitidine . The single chemotherapy regimen consisted of zometa and docetaxel, each in 2 patients (50%). The 4-cycle combination regimen was dominated by doxorubicin + cyclophosphamide in 15 patients (45%), while the 6-cycle regimen was mostly doxorubicin + cyclophosphamide + paclitaxel in 47 patients (94%). Conclusion: The study showed that all patients received pre- chemotherapy therapy and the chemotherapy pattern was dominated by anthracycline and taxane -based combinations.

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