SKRINING FITOKIMIA DAN UJI TOKSISITAS EKSTRAK ASETON DAUN SIRSAK (Annona muricata L.) TERHADAP LARVA Artemia salina Leach

RACHELNIA RACHMASARI, NIM. C11600045 (2020) SKRINING FITOKIMIA DAN UJI TOKSISITAS EKSTRAK ASETON DAUN SIRSAK (Annona muricata L.) TERHADAP LARVA Artemia salina Leach. Masters thesis, STIKES MUHAMMADIYAH GOMBONG.

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Abstract

Introduction : The soursop (Annona muricata L.) is a medicinal plant that belongs to the family Annonaceae. Soursop leaves contain flavonoids, saponins, tannins and several other chemical contents including acetogenin which have cytotoxic potential. Objective : This study aims to determine the potential acute toxicity of soursop leaf extract (Annona muricata L.) against Artemia salina Leach larva. Methode : The research used was the Brine Shrimp Lathality Test (BSLT) using 10 larvae of Artemia salina Leah divided into 4 treatment concentrations, 5 μg / mL, 10 μg / mL, 20 μg / mL, 30 μg / mL and 1 negative control and 3 replications Result : Larva mortality was calculated after 24 hours by probit analysis, the LC50 value of 10.5 μg / mL. Conculsion : Toxicity test on soursop leaf (Annona muricata L.) acetone extract has very toxic potential, because the LC50 value <1000 μg / mL.

Item Type:	Thesis (Masters)
Additional Information:	Apt. Titi Pudji Rahayu, M..Farm; Apt. Naelaz Zukhruf W.K, M. Parm. Sci
Uncontrolled Keywords:	Annona muricata L., toxicity, Brine Shrimp Lathality Test, LC50; Annona muricata L., toksisitas, Brine Shrimp Lathality Test, LC50
Subjects:	S1 Farmasi
Depositing User:	DWI SUNDARIYATI S.I.Pust
Date Deposited:	10 Nov 2021 03:11
Last Modified:	10 Nov 2021 03:11
URI:	http://repository.unimugo.ac.id/id/eprint/1485

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