NURLAELA RAHMAWATI, NIM. C2019034 (2023) UJI SITOTOKSIK EKSTRAK ETIL ASETAT DAN EKSTRAK ASETON KULIT MELINJO MERAH (Gnetum gnemon L) TERHADAP LARVA UDANG Artemia salina Leach DENGAN MENGGUNAKAN METODE BRINE SHRIMP LETHALITY TEST (BSLT). Skripsi thesis, UNIVERSITAS MUHAMMADIYAH GOMBONG.
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Abstract
Background: cancer is disease that is not infectious And become burden health in most of the world. Treatment cancer resulted Lots impact effect side that doesn't The same And No fun. Effect side treatment cancer has push various research conducte. For look for alternative new in treatment cancer that is form plant skin melinjo red (Gnetum gnemon L). Skin Melinjo Red (Gnetum gnemon L) contains component compound stilbenoid as cytotoxic . Purpose: research is know activity cytotoxic on extract ethyl acetate And acetone skin melinjo red (Gnetum gnemon L) with LC50 on Artemia Leach. Methods: this research was initiated with standardization extracts that consist from water level, rate total ash, and rate ash No late acid, screening phytochemicals (alkaloid, flavonoid, tannin, saponin, and TLC tests). Stage furthermore done test BSLT cytotoxic with count LC50 . Results; research Results extract ethyl acetate And acetone positive contains alkaloids, flavonoids, tannins, and negative contain saponins. Test standardization extract ethyl acetate And acetone consecutive that is water content 8 .16 % and 8.82%; rate total ash 3.18% and 3.23%; rate ash No late acid 0.605% and 0.69%. On level toxicity extract ethyl acetate Skin Melinjo Red (Gnetum gnemon L) shows characteristic toxic with LC50 58,39 μg/mL and extract acetone of 40,48 μg/mL showed characteristic toxic currently against Artemia larvae copy Leach. Conclusion: on extract ethyl acetate have characteristic toxic And extract acetone have characteristic toxic medium . Recommendation: necessary done study more carry on with use method test different cytotoxics. And need done test toxicity on extract ethyl acetate and acetone skin melinjo red.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | apt. Titi Pudji Rahayu, M.Farm; apt. Naelaz Zukhruf W.K., M.Pharm.Sci |
| Uncontrolled Keywords: | skin melinjo red; stilbenoid; cytotoxic; LC50; BSLT; kulit melinjo merah; sitotoksik |
| Subjects: | S1 Farmasi |
| Divisions: | Prodi Farmasi S1 |
| Depositing User: | Desy Setiyawati - |
| Date Deposited: | 11 Nov 2023 07:20 |
| Last Modified: | 11 Nov 2023 07:20 |
| URI: | http://repository.unimugo.ac.id/id/eprint/2902 |
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