KARINA AFAF PUTRI, NIM. C12020025 (2024) GAMBARAN INTERAKSI OBAT PADA PASIEN RAWAT JALAN PENYAKIT JANTUNG KORONER DI RUMAH SAKIT PKU MUHAMMADIYAH GOMBONG TAHUN 2023. Skripsi thesis, UNIVERSITAS MUHAMMADIYAH GOMBONG.
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Abstract
Background: Coronary Heart Disease (CHD) or often called PJK in Indonesia is reported to be the first disease that causes death by 26.4%. In PJK patients, it is usually accompanied by comorbidities, so it requires a lot of drugs for therapy. The use of various drugs can cause drug interactions. The occurrence of drug interactions can cause treatment problems, increase costs and interfere with the effectiveness of treatment. Objective: This study aims to determine the description of drug interactions in outpatients with coronary heart disease at PKU Muhammadiyah Gombong Hospital in 2023. Methods: This study used a non-experimental descriptive method retrospectively with a purposive sampling method. The drug data obtained were analyzed using the Medscape and Drugs.com applications. The number of samples included in the inclusion criteria was 230. Result: The results obtained showed that out of 230 patients, 223 (97%) patients had the potential to experience drug interactions. The majority of drug interactions that occurred based on severity were at a Moderat level of 652 cases (82%) most commonly occurs with aspirin and bisoprolol, minor 83 cases (10%) The most common interaction between aspirin and furosemide, and major 57 cases (7%). Based on the most common drug interaction mechanism, interactions with pharmacodynamic mechanisms occurred with 52 cases (58,43%), pharmacokinetics 7 cases (7.87%) Conclusion: Drug interactions that occurred in outpatients with coronary heart disease at the PKU Muhammadiyah Gombong Hospital mostly occurred at a Moderat level of severity of 652 cases (82%), based on the most common drug interaction mechanism occurred in the pharmacodynamic drug interaction mechanism of 52 cases (58,43%). Recommendation: For further researchers, conducting prospective research on patients can provide detailed information regarding drug interactions.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | apt. Chondrosuro Miyarso., M.Clin.Pharm.;apt. Anwar Sodik., M.Farm. |
| Uncontrolled Keywords: | Coronary Heart Disease, drug interaction, outpatients;Penyakit Jantung Koroner (PJK), interaksi obat, pasien rawat jalan |
| Subjects: | S1 Farmasi |
| Depositing User: | Unnamed user with email stikesmuhgombong@yahoo.com1 |
| Date Deposited: | 30 Oct 2024 03:16 |
| Last Modified: | 30 Oct 2024 03:16 |
| URI: | http://repository.unimugo.ac.id/id/eprint/3542 |
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