LINA KHUSNIA, NIM. C12020028 (2024) RASIONALITAS PENGGUNAAN ANTIEMETIK PADA PASIEN KANKER PAYUDARA YANG MENJALANI KEMOTERAPI DI RUMAH SAKIT PKU MUHAMMADIYAH GOMBONG TAHUN 2023. Skripsi thesis, UNIVERSITAS MUHAMMADIYAH GOMBONG.
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Abstract
Background: Breast cancer is one of the leading causes of death and remains prevalent in Indonesia. Chemotherapy is currently a treatment option for breast cancer with side effects such as nausea and vomiting. Chemotherapy-induced nausea and vomiting can be prevented with antiemetic therapy. Irrational use of antiemetics can reduce the quality of life for patients. Objective: This study aims to describe the use of antiemetics and evaluate the rationality of their use in breast cancer patients undergoing chemotherapy at PKU Muhammadiyah Gombong Hospital in 2023. Methods: This study used a retrospective non-experimental descriptive method with total sampling. Drug data obtained were compared with the National Comprehensive Cancer Network (NCCN): Guideline on Antiemetics 2023. Result: The study found that the antiemetics used in breast cancer patients undergoing chemotherapy at PKU Muhammadiyah Gombong Hospital in 2023 were a combination of ondansetron, dexamethasone, ranitidine, and diphenhydramine (100.00%). Evaluation results showed appropriate indication criteria (100.00%), appropriate drug selection (100.00%), appropriate dose (75.37%), appropriate route of administration (100.00%), and appropriate dosing interval (100.00%). Conclusion: The use of antiemetics for breast cancer treatment undergoing chemotherapy at PKU Muhammadiyah Gombong Hospital in 2023 is still not rational when considering the doses of medication used. Recommendation: For future research, it is recommended to evaluate patient compliance and response to nausea and vomiting in breast cancer patients undergoing chemotherapy.
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | apt. Chondrosuro Miyarso, M.Clin.Pharm; apt. Anwar Sodik, M.Farm |
| Uncontrolled Keywords: | rationality; antiemetics; breast cancer; rasionalitas; antiemetik; kanker payudara |
| Subjects: | S1 Farmasi |
| Divisions: | Prodi Farmasi S1 |
| Depositing User: | Unnamed user with email [email protected] |
| Date Deposited: | 07 Feb 2025 07:29 |
| Last Modified: | 07 Feb 2025 07:29 |
| URI: | http://repository.unimugo.ac.id/id/eprint/3752 |
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