SRI FATONAH, NIM. C11700121 (2021) FORMULASI DAN EVALUASI SEDIAAN FACIAL WASH EKSTRAK ETANOL DAUN SIRSAK (Annona muricata L.) SEBAGAI ANTIOKSIDAN DENGAN METODE DPPH (1,1-diphenyl -2-picrylhydrazyl). Skripsi thesis, UNIVERSITAS MUHAMMADIYAH GOMBONG.
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Abstract
Background, soursop leaf (Annona muricata L.) is one of the plants that be used as an antioxidant. Research purpose, this study aims to determine the formula that has good physical properties with different concentrations of gelling agent and to determine the antioxidant activity of soursop leaf ethanol extract in facial wash preparations. Methods, this research was conducted using the DPPH (1,1 diphenyl-2- picrylhydrazil) free radical immersion method with a UV-Vis spectrophotometer at a wavelength of 517 nm. Antioxidant activity test were carried out at concentrations of 20 ppm, 40 ppm, 60 ppm and 80 ppm. The principle of the DPPH method is that there is a decrease in the increase in the absorbanse value which is propotional to the increase in the concentration of antioxidant compounds expressed in I . Result, The result of the evaluastion physical properties of the facial wash preparations of soursop keaf ethanol extract in formulas 1,2 dan 3 met the organoleptic, homogeneity and viscosity. Formulas 2 and 3 met the pH and spreadability and only formula 3 met the irritation test. Formula 3 is the most preferred preparation based on the hedonic test. Antioxidant activity was tested on formula 3 facial wash preparations of soursop leaf ethanol extract. The result of I obtained is 34,13 ppm which is a very strong antioxidant category. Conclusion, carbopol 940 as a gelling agent can affect of facial eash preparations of soursop leaf ethanol extract with p<0,05. Formula 3 which is the preparation with the best physical has a very strong antioxidant activity. Recommedations, recommedations from test studies are that it is necessary to do further research on antioxidant activity with different methods
| Item Type: | Thesis (Skripsi) |
|---|---|
| Additional Information: | Apt. Titi Pudji Rahayu, M.Farm; Apt. Naelaz Zukhruf.WK, M.Pharm.Sci |
| Uncontrolled Keywords: | Soursop leaf, Carbopol 940, Antioxidant, DPPH; Daun Sirsak, Karbopol 940, Antioksidan, DPPH |
| Subjects: | S1 Farmasi |
| Depositing User: | DWI SUNDARIYATI S.I.Pust |
| Date Deposited: | 31 May 2022 03:26 |
| Last Modified: | 31 May 2022 03:26 |
| URI: | http://repository.unimugo.ac.id/id/eprint/1730 |
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